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Lynne Quarmby is a Canadian scientist, activist, and politician. She is a professor and Chair of the Department of Molecular Biology and Biochemistry at Simon Fraser University in Burnaby, British Columbia. She was a candidate for the Green Party of Canada in Burnaby North—Seymour in the 2015 federal election, and is the Green Party of Canada's Science Policy Critic. ==Research and education== Quarmby completed a BSc in Marine Biology and a MSc in Biological Oceanography at the University of British Columbia before moving to the University of Connecticut to complete her PhD in Biochemistry.〔(【引用サイトリンク】url=http://www.sfu.ca/mbb/People/Quarmby/ )〕 She worked as a postdoctoral fellow in the lab of Nobel laureate Alfred Gilman at the University of Texas Southwestern Medical Center in Austin, TX, then in the lab of Criss Hartzell at Emory University in Atlanta, GA, where she also held her first faculty position. She moved her lab to Simon Fraser University in 2000. Quarmby's research has been aimed at understanding the signals and mechanisms of deflagellation, the process by which cells shed their cilia into the environment. Cilia are found on most eukaryotic cells and on most cells in the human body, and defects in a cell's ability to form or maintain its cilia can cause diseases known as ciliopathies, that may include symptoms such as cystic kidney disease, blindness, and obesity. Through her research using the single-celled ciliated green alga Chlamydomonas reinhardtii as a model organism, Quarmby identified members of the NIMA-related family of serine/threonine kinases that function in deflagellation as well as in the assembly and maintenance of cilia.〔(【引用サイトリンク】url=http://www.ncbi.nlm.nih.gov/pubmed/?term=%22Quarmby+LM%22%5BAuthor%5D+nima )〕 Her group went on to show that NEK8 localizes to cilia, and that mutations in NEK8 interfere with its ciliary localization and cause a severe juvenile cystic kidney disease known as nephronophthisis, underscoring the important link between cilia and cystic kidney disease. Quarmby's work has been funded by the Natural Sciences and Engineering Research Council of Canada (NSERC), the Canadian Institutes for Health Research (CIHR), and the Kidney Foundation of Canada (KFoC).〔(【引用サイトリンク】website=Canadian Research Information System )〕〔(【引用サイトリンク】url=http://www.kidney.ca/document.doc?id=83 )〕 In 2011 NSERC recognized Quarmby's research program by awarding her a Discovery Accelerator Supplement, a funding program reserved for researchers who show strong potential to become international leaders within their field.〔(【引用サイトリンク】url=http://www.nserc-crsng.gc.ca/NSERC-CRSNG/FundingDecisions-DecisionsFinancement/DiscoveryAcceleratorSupplements-SupplementsAccelerationDecouverte/index_eng.asp?Year=2011 )〕 Quarmby is known for outstanding undergraduate teaching, and received a SFU Teaching Excellence Award in 2011. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lynne Quarmby」の詳細全文を読む スポンサード リンク
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